Diets with high-fat cheese, high-fat meat, or carbohydrate on cardiovascular risk markers in overweight postmenopausal women: a randomized crossover trial

Share This Post

Share on facebook
Share on linkedin
Share on twitter
Share on email

URL: https://academic.oup.com/ajcn/article/102/3/573/4564305

Journal: The American Journal of Clinical Nutrition

Publication Date: 09/2015

Summary: Heart associations recommend limited intake of sat- urated fat. However, effects of saturated fat on low-density lipopro- tein (LDL)-cholesterol concentrations and cardiovascular disease risk might depend on nutrients and specific saturated fatty acids (SFAs) in food.  We explored the effects of cheese and meat as sources of SFAs or isocaloric replacement with carbohydrates on blood lipids, lipoproteins, and fecal excretion of fat and bile acids. The study was a randomized, crossover, open-label in- tervention in 14 overweight postmenopausal women. Three full- diet periods of 2-wk duration were provided separated by 2-wk washout periods. The isocaloric diets were as follows: 1) a high- cheese (96–120-g) intervention [i.e., intervention containing cheese (CHEESE)], 2) a macronutrient-matched nondairy, high- meat control [i.e., nondairy control with a high content of high-fat processed and unprocessed meat in amounts matching the satu- rated fat content from cheese in the intervention containing cheese (MEAT)], and 3) a nondairy, low-fat, high-carbohydrate control (i.e., nondairy low-fat control in which the energy from cheese fat and protein was isocalorically replaced by carbohydrates and lean meat (CARB).  The CHEESE diet caused a 5% higher high-density lipo- protein (HDL)-cholesterol concentration (P = 0.012), an 8% higher apo A-I concentration (P , 0.001), and a 5% lower apoB:apo A-I ratio (P = 0.008) than did the CARB diet. Also, the MEAT diet caused an 8% higher HDL-cholesterol concentration (P , 0.001) and a 4% higher apo A-I concentration (P = 0.033) than did the CARB diet. Total cholesterol, LDL cholesterol, apoB, and triacyl- glycerol were similar with the 3 diets. Fecal fat excretion was 1.8 and 0.9 g higher with the CHEESE diet than with CARB and MEAT diets (P , 0.001 and P = 0.004, respectively) and 0.9 g higher with the MEAT diet than with the CARB diet (P = 0.005). CHEESE and MEAT diets caused higher fecal bile acid excretion than did the CARB diet (P , 0.05 and P = 0.006, respectively). The dominant type of bile acids excreted differed between CHEESE and MEAT diets.
Diets with cheese and meat as primary sources of SFAs cause higher HDL cholesterol and apo A-I and, therefore, appear to be less atherogenic than is a low-fat, high-carbohydrate diet. Also, our findings confirm that cheese increases fecal fat excretion.

Share This Post

Share on facebook
Share on linkedin
Share on twitter
Share on email

Subscribe To Our Newsletter

Get Fun Carnivore Updates and inspirations

Leave a Comment

Your email address will not be published. Required fields are marked *

More To Explore

Meat and mental health: A meta-analysis of meat consumption, depression, and anxiety

URL: https://www.tandfonline.com/doi/full/10.1080/10408398.2021.1974336 Journal: Critical Reviews in Food Science and Nutrition Publication Date: 10/2021 Summary: In this meta-analysis, we examined the quantitative relation between meat consumption or avoidance, depression, and anxiety. in June 2020, we searched five online databases for primary studies examining differences in depression and anxiety between meat abstainers and meat consumers that offered a

Effect of Lower Versus Higher Red Meat Intake on Cardiometabolic and Cancer Outcomes: A Systematic Review of Randomized Trials

URL: https://annals.org/aim/fullarticle/2752326/effect-lower-versus-higher-red-meat-intake-cardiometabolic-cancer-outcomes Journal: Annals of Internal Medicine Publication Date: 10/2019 Summary: Low- to very-low-certainty evidence suggests that diets restricted in red meat may have little or no effect on major cardiometabolic outcomes and cancer mortality and incidence.

Do You Want To Achieve your Optimal Health?

Join us for a free 30-date trial. Cancel Anytime.